Appointment
Appointment
  • 773-775-0300Call today!
  • 6560 W Higgins Ave.Chicago, Illinois
Appointment

Cantharidin – Beetlejuice to Kill the Wart

One of the in-office treatment options for plantar warts includes Cantharidin (Canthrone), a blistering agent or vesicant (vesicle is the medical term for blister, so a vesicant is a blister maker) made from an odorless, colorless compound secreted from over 1500 species of blister beetles.(1,2)

Beetlejuice

As a kid, I watched the cartoon Beetlejuice, an American-Canadian cartoon loosely based on the 1988 film of the same name (starring Michael Keaton and Alec Baldwin). and so dedicate this blogpost to the makers of that entertaining kid’s show  This Tim Burton cartoon series focuses on the life of a “goth girl, Lydia Deetz and her undead friend Beetlejuice as they explore The Neitherworld, a wacky afterlife realm inhabited by monsters, ghosts, ghouls and zombies. As in the film, Lydia could summon Beetlejuice out of the Neitherworld (or go there herself) by calling his name three times, sometimes as part of a set chant:

“Though I know I should be wary,
Still I venture someplace scary;
Ghostly hauntings I turn loose …
Beetlejuice, Beetlejuice, Beetlejuice!” (3)

Because this compound works so well on warts, we don’t even need to jokingly create a chant that finishes with, “Beetlejuice, Beetlejuice, Beetlejuice!” because the wart disappears!

Treatment
After trimming down the callus with a scalpel, Cantharidin is applied to the wart and covered with an occlusive dressing for 24 hours. Although this in office treatment does not hurt, the treatment causes a blister to form. This blistering may cause pain. In college, I had this treatment performed on my plantar warts. For me, the blistering was the worst part of the plantar wart treatment. Granted, I was experiencing pain prior to seeing the podiatrist and within four weeks the warts were gone. Scarring does not occur due to how the medication interacts with the skin (see below – Mechanism of Action). I was part of the 80% of cases in which this treatment will cure the wart.4 Occasionally, this treatment may take reapplication every 2 weeks. A two-month period of watching for signs of regrowth should be undertaken before officially calling the wart cured.

How it works – Mechanism of Action
The skin is made up of many layers as shown below. The outer layer, or epidermis is where the medication is absorbed. Cantharidin is absorbed by the lipid layers that layer. Then, the medication activates an enzyme, a neutral serine protease, that causes the breakdown of the intercellular connections, a process called acantholysis. Since this happens in the outer layer of skin, scarring will not occur.(1) And because the 1988 Beetlejuice film was in the Horror-film category, may I wish you an early Happy Halloween!

References:
1. Moed L, Shwayder A, Chang MW. Cantharidin Revisited – A Blistering Defense of an Ancient Medicine. Arch Dermatol. 2001;137(10):1357-1360
2. https://en.wikipedia.org/wiki/Cantharidin
3. https://en.wikipedia.org/wiki/Beetlejuice_(TV_series)

Images:
www.toon opedia.com

  • Share this post

Previous Article Plantar Warts – Home Remedy Approach
Next Article Plantar warts - CO2 Laser and Surgical Excision

Comments

  1. “There was a guy [url=http://www.wholesalejerseys.us.org/]Wholesale China Jerseys[/url] standing over there about a head taller than everybody else saluting during the anthem and it kind of got my attention,” Tomlin [url=http://www.jerseyschina.us.org/]China Jerseys Wholesale[/url] said. “I wanted to know about this enormous human being over there saluting.”
    Wholesale Hockey Jerseys Online [url=http://www.nhloutlet.us.com/]Wholesale Hockey Jerseys Online[/url]

  2. Peterson’s contract includes a $250,000 workout bonus, but he doesn’t actually start collecting his $12.75 million salary [url=http://www.stitchedjerseyswholesale.com/]Cheap Wholelsale Football jerseys[/url] until games start in September.
    Swell Bottles Wholesale [url=http://www.swellwaterbottlesale.com/]Swell Bottles Wholesale[/url]

  3. “Where it goes from here, I don’t have that answer right now,” Baalke told reporters before practice. “I don’t have enough information regarding the situation right now. All I can speak of is today and today Ahmad is away from this football team.”
    Nike Blazers Shoes Sale

  4. If you are seeking for the top service to get website visitors to your web page, i advise to use seowebsitetrafficnet. I am using it with a great result. Simply just type seowebsitetrafficnet in google.

  5. Thanks on your marvelous posting! I quite enjoyed reading
    it, you may be a great author. I will make certain to bookmark your blog
    and will often come back someday. I want to encourage one to continue your great
    writing, have a nice weekend!

  6. Suhagraat me sambhog sex ko start karne se pehle aap ko some time tak apni .. of the students of Imam Jafar Sadiq A. You can also save lots of time and money. hindi, tamil, telugu and kannada with images for quick reference A fruit, root,
    how to save money for a trip fast

  7. Hey there! I’m at work browsing your blog from my new
    iphone! Just wanted to say I love reading through your blog and
    look forward to all your posts! Carry on the fantastic work!

  8. I believe this is among the most significant info for me.
    And i am satisfied studying your article.
    However wanna commentary on some basic issues, The website taste is great,
    the articles is in point of fact great : D. Excellent process,
    cheers

  9. I was curious if you ever considered changing the layout of your blog? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having 1 or 2 pictures. Maybe you could space it out better?

Leave a Comment